Expression and Clinical Significance of Long Non-Coding Ribonucleic Acid LOC554202 and H19 in Serum of Cervical Cancer

نویسندگان

چکیده

To explore the serum expression of long non-coding ribonucleic acid H19 and LOC554202 in cervical cancer as well clinical significance is main objective. Serum samples were collected from 52 preoperative patients, at same time, also 39 agematched women admitted due to gynecological benign diseases with screening negative selected control group. Among them, 10 patients used for postoperative comparisons. The levels above specimens detected through real-time quantitative reverse transcription-polymerase chain reaction before after surgery compared. Meanwhile, relationships their pathological parameters analyzed receiver operating characteristic curve was adopted evaluate diagnostic efficiency levels. apparently elevated compared those group, markedly declined relative surgery, difference statistical (p<0.05). not correlated age, type, classification area under curve, sensitivity specificity independently diagnosing 0.661, 30.8 % 94.9 %, respectively, while 0.707, 69.2 66.7 respectively. can serve potential circulatory markers diagnosis monitoring cancer.

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ژورنال

عنوان ژورنال: Indian Journal of Pharmaceutical Sciences

سال: 2022

ISSN: ['0250-474X', '1998-3743']

DOI: https://doi.org/10.36468/pharmaceutical-sciences.spl.515